Description

(S)-(-)-Alpha,α-Diphenyl-2-Pyrrolidinyl Methyltms Ether is a high-value, chiral organosilicon compound featuring a pyrrolidine core. This chemical is a critical synthetic intermediate, prized for its role in constructing complex molecules with defined stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries engaged in asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block in the asymmetric synthesis of drug candidates and active pharmaceutical ingredients (APIs).
• Catalyst Ligand Precursor: Used in the preparation of sophisticated ligands for transition metal-catalyzed reactions, such as cross-couplings and enantioselective hydrogenations.
• Fine Chemical Synthesis: Employed in the research and production of complex, high-value specialty chemicals requiring precise stereocontrol.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological development in organic and medicinal chemistry research.

Basic Information

Product Name	(S)-(-)-Alpha,α-Diphenyl-2-Pyrrolidinyl Methyltms Ether
CAS No.	848821-58-9
Molecular Formula	C24H29NOSi
Molecular Weight	375.58 g/mol
Synonyms	(S)-(-)-2-(Diphenylhydroxymethyl)-1-methylpyrrolidine trimethylsilyl ether; (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether; (S)-(-)-2-(Diphenylhydroxymethyl)-N-methylpyrrolidine TMS ether; (S)-(-)-DPMP-TMS ether; (S)-(-)-α,α-Diphenyl-2-pyrrolidinylmethyl trimethylsilyl ether; (S)-(-)-α,α-Diphenyl-2-(trimethylsilyloxymethyl)pyrrolidine; (S)-(-)-1-Methyl-2-(diphenylhydroxymethyl)pyrrolidine TMS ether
EINECS	Contact for details

Quality Control

Our (S)-(-)-Alpha,α-Diphenyl-2-Pyrrolidinyl Methyltms Ether is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.