Description

(5-Methyl-1,3-thiazol-4-yl)methanol is a versatile heterocyclic building block featuring a thiazole core substituted with a hydroxymethyl group. This compound is of significant commercial interest as a key synthetic intermediate in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation fungicides, herbicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-rich thiazole moiety.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and fluorescent tags used in biochemical and diagnostic research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	(5-Methyl-1,3-thiazol-4-yl)methanol
CAS No.	848774-94-7
Molecular Formula	C5H7NOS
Molecular Weight	129.18 g/mol
Synonyms	4-(Hydroxymethyl)-5-methyl-1,3-thiazole; 5-Methyl-4-thiazolemethanol; 5-Methylthiazole-4-methanol; (5-Methyl-4-thiazolyl)methanol; 4-Hydroxymethyl-5-methylthiazole; 5-Methyl-1,3-thiazol-4-ylmethanol; 5-Methyl-4-thiazolecarbinol
EINECS	Contact for details

Quality Control

Our (5-Methyl-1,3-thiazol-4-yl)methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can supply material compliant with various pharmacopeial standards (e.g., USP/EP) for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.