Description

6-Bromo-1,3-Dihydro-Indole-2-Thione is a versatile sulfur-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key precursor for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, where it serves as a crucial intermediate for creating new drug candidates and biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials and functional dyes due to its electron-rich indole-thione structure.
• Chemical Biology: Employed as a probe or scaffold in the design of enzyme inhibitors and receptor modulators for biological studies.
• Academic & Contract Research: Essential for methodological development and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	6-Bromo-1,3-Dihydro-Indole-2-Thione
CAS No.	848649-94-5
Molecular Formula	C8H6BrNS
Molecular Weight	228.11 g/mol
Synonyms	6-Bromo-2,3-dihydro-1H-indole-2-thione; 6-Bromoindoline-2-thione; 6-Bromo-1,3-dihydro-2H-indole-2-thione; 2-Thioxo-6-bromo-2,3-dihydro-1H-indole; 6-Bromo-2-indolinethione; 6-Bromo-2-mercaptoindoline; 6-Bromoindole-2-thiol (tautomeric form)
EINECS	Contact for details

Quality Control

Our 6-Bromo-1,3-Dihydro-Indole-2-Thione is produced under a strict quality management system to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.