Description

N,α-Dimethyl-β-[[(10R)-10-(Trimethylsilyl)-9-Borabicyclo[3.3.2]Dec-9-Yl]Oxy]-(αs,βs)-Benzeneethanamine is a sophisticated, chiral organoboron reagent designed for high-precision asymmetric synthesis. This compound matters as a highly selective chiral ligand or catalyst precursor, enabling the construction of complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring enantioselective control.

Application

• Asymmetric Catalysis: As a chiral ligand or catalyst precursor in enantioselective C-C and C-X bond-forming reactions, such as hydroborations and conjugate additions.
• Pharmaceutical Intermediate Synthesis: For the stereocontrolled synthesis of chiral building blocks and advanced intermediates in API development.
• Agrochemical Research: In the development of enantiomerically pure active ingredients for herbicides, fungicides, and insecticides.
• Material Science: For the synthesis of chiral polymers or organic frameworks with specific optical or electronic properties.
• Methodology Development: A key reagent in academic and industrial R&D for discovering new catalytic asymmetric transformations.
• Process Chemistry: Scaling up enantioselective synthetic routes for commercial production in fine chemical manufacturing.

Basic Information

Product Name	N,α-Dimethyl-β-[[(10R)-10-(Trimethylsilyl)-9-Borabicyclo[3.3.2]Dec-9-Yl]Oxy]-(αs,βs)-Benzeneethanamine
CAS No.	848618-13-3
Molecular Formula	C21H38BNOSi
Molecular Weight	359.43 g/mol
Synonyms	(αS,βS)-N,α-Dimethyl-β-[[(10R)-10-(trimethylsilyl)-9-borabicyclo[3.3.2]dec-9-yl]oxy]benzenethanamine; (S,S)-N-Methyl-1-[[(10R)-10-(trimethylsilyl)-9-borabicyclo[3.3.2]dec-9-yl]oxy]-1-phenyl-2-propanamine; (S,S)-N-Methyl-1-((10R)-10-(trimethylsilyl)-9-borabicyclo[3.3.2]decan-9-yloxy)-1-phenylpropan-2-amine; Chiral BBD Amine Derivative; (S,S)-N-Methyl-BBD-Amine-O-TMS; Asymmetric Boronate Ester Amine Ligand
EINECS	Contact for details

Quality Control

Our N,α-Dimethyl-β-[[(10R)-10-(Trimethylsilyl)-9-Borabicyclo[3.3.2]Dec-9-Yl]Oxy]-(αs,βs)-Benzeneethanamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen) due to its moisture-sensitive and light-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.