Description

1-Boc-4-Carboxyindole is a high-purity, protected indole derivative essential for advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and versatile building block for constructing complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of drug candidates, particularly those targeting neurological and oncological pathways.
• Peptidomimetic Synthesis: Used to incorporate the indole scaffold into peptide-like structures for drug discovery.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Precursor for specialty polymers and advanced organic materials with specific electronic properties.
• Academic & R&D: Fundamental reagent in medicinal chemistry and organic synthesis research laboratories.
• Custom Synthesis: Starting material for the contract manufacturing of complex, bespoke organic molecules.

Basic Information

Product Name	1-Boc-4-Carboxyindole
CAS No.	848444-79-1
Molecular Formula	C₁₄H₁₅NO₄
Molecular Weight	261.27 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-1H-indole-4-carboxylic acid; 1-Boc-indole-4-carboxylic acid; tert-Butyl 4-carboxy-1H-indole-1-carboxylate; 4-Carboxy-1H-indole-1-carboxylic acid tert-butyl ester; 1H-Indole-4-carboxylic acid, 1-[(1,1-dimethylethoxy)carbonyl]-; Boc-4-indolecarboxylic acid; 1-Boc-4-indolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Carboxyindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.