Description

(S)-2-Chloro-5,6,7,8,9,10-Hexahydrocyclohepta[B]Indole-6-Carboxamide is a high-purity, chiral synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly those targeting complex neurological and metabolic pathways. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require enantiomerically pure intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs) with potential central nervous system (CNS) activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route scouting for new chemical entities (NCEs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development of complex molecules.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	(S)-2-Chloro-5,6,7,8,9,10-Hexahydrocyclohepta[B]Indole-6-Carboxamide
CAS No.	848193-72-6
Molecular Formula	C14H15ClN2O
Molecular Weight	262.74 g/mol
Synonyms	(6S)-2-Chloro-6,7,8,9,10,11-hexahydro-5H-cyclohepta[b]indole-6-carboxamide; (S)-2-Chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxylic acid amide; UNII-6J8K4S8H4P; 6J8K4S8H4P; CHEMBL3183450; AKOS015915923; (S)-2-Chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide
EINECS	Contact for details

Quality Control

Our (S)-2-Chloro-5,6,7,8,9,10-Hexahydrocyclohepta[B]Indole-6-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research-grade and development-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The material should be handled under an inert atmosphere if prolonged exposure is anticipated during use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.