Description

7-Bromo-3-Methyl-1,2,3,4-Tetrahydroisoquinoline is a versatile brominated tetrahydroisoquinoline derivative, a key heterocyclic scaffold of significant interest in advanced organic synthesis. This compound matters as a crucial pharmaceutical intermediate and building block for medicinal chemistry research, enabling the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates targeting neurological disorders, cardiovascular diseases, and oncology.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its modifiable bromine and tetrahydroisoquinoline core.
• Agrochemical Research: Serves as a key synthon in developing new active ingredients for crop protection products.
• Ligand and Catalyst Development: Utilized in the preparation of novel nitrogen-containing ligands for asymmetric catalysis and metal complexes.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Academic and Contract Research: Employed in university and CRO laboratories for fundamental research in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	7-Bromo-3-Methyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	848185-12-6
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	7-Bromo-3-methyl-1,2,3,4-tetrahydroisoquinoline; 3-Methyl-7-bromo-1,2,3,4-tetrahydroisoquinoline; 7-Bromo-3-methyl-3,4-dihydro-1H-isoquinoline; 1,2,3,4-Tetrahydro-7-bromo-3-methylisoquinoline; 848185-12-6; 7-Br-3-Me-THIQ
EINECS	Contact for details

Quality Control

Our 7-Bromo-3-Methyl-1,2,3,4-Tetrahydroisoquinoline is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.