Description

Ethyl 5-(4-Fluorophenyl)-2-thiophenecarboxylate is a high-purity organic building block featuring a fluorinated phenyl-thiophene core. This compound is a critical intermediate in modern pharmaceutical and advanced materials research, valued for its unique molecular architecture that enables the synthesis of complex target molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity of the fluorinated thiophene moiety.
• Material Science Research: Serves as a precursor for organic semiconductors, OLED (Organic Light-Emitting Diode) materials, and conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags and molecular probes for diagnostic and imaging applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production projects.
• Academic & Industrial R&D: A versatile starting material for methodological development and exploration of new chemical spaces in organic chemistry.

Basic Information

Product Name	Ethyl 5-(4-Fluorophenyl)-2-thiophenecarboxylate
CAS No.	848095-02-3
Molecular Formula	C13H11FO2S
Molecular Weight	250.29 g/mol
Synonyms	Ethyl 5-(4-fluorophenyl)thiophene-2-carboxylate; 5-(4-Fluorophenyl)-2-thiophenecarboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic acid, 5-(4-fluorophenyl)-, ethyl ester; Ethyl 5-(p-fluorophenyl)thiophene-2-carboxylate; 848095-02-3; AKOS BRN 0971; SCHEMBL15406279; ZINC000068048758
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-(4-Fluorophenyl)-2-thiophenecarboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.