Description

4-(3-(Trifluoromethyl)Phenyl)Thiazole-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and trifluoromethylphenyl motifs.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated structure.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific scaffold.

Basic Information

Product Name	4-(3-(Trifluoromethyl)Phenyl)Thiazole-2-Carboxylic Acid
CAS No.	847956-11-0
Molecular Formula	C11H6F3NO2S
Molecular Weight	273.23 g/mol
Synonyms	2-Thiazolecarboxylic acid, 4-[3-(trifluoromethyl)phenyl]-; 4-(3-(Trifluoromethyl)phenyl)-1,3-thiazole-2-carboxylic acid; 4-(α,α,α-Trifluoro-m-tolyl)-2-thiazolecarboxylic acid; 4-(3-Trifluoromethylphenyl)thiazole-2-carboxylic acid; 847956-11-0; AKOS005258213; FT-0773296; NS00023827; SCHEMBL15547695; ZINC000257830511
EINECS	Contact for details

Quality Control

Our 4-(3-(Trifluoromethyl)Phenyl)Thiazole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.