Description

1H-Indole-3-Acetonitrile, 5-Fluoro-A,A-Dimethyl- CAS NO 847865-44-5 is a high-purity, fluorinated indole derivative, a crucial building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which serves as a versatile intermediate for creating complex molecules with targeted biological activity. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, leveraging the fluorine atom for enhanced efficacy and environmental profile.
• Chemical Research: Serves as a versatile scaffold in academic and industrial laboratories for exploring novel heterocyclic chemistry and structure-activity relationships (SAR).
• Material Science Precursor: Potential use in the synthesis of specialized organic electronic materials and advanced polymers.

Basic Information

Product Name	1H-Indole-3-Acetonitrile, 5-Fluoro-A,A-Dimethyl- CAS NO 847865-44-5
CAS No.	847865-44-5
Molecular Formula	C₁₂H₁₁FN₂
Molecular Weight	202.23 g/mol
Synonyms	5-Fluoro-α,α-dimethyl-1H-indole-3-acetonitrile; 5-Fluoro-α,α-dimethylindole-3-acetonitrile; 5-Fluoro-2,2-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile; (5-Fluoro-1H-indol-3-yl)-2-methylpropanenitrile; 847865-44-5; 5-Fluoro-α,α-dimethyl-1H-indole-3-acetic acid nitrile
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Acetonitrile, 5-Fluoro-A,A-Dimethyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.