Description

Boronic Acid, [4-(Mercaptomethyl)Phenyl]- (9Ci) is a specialized bifunctional organoboron compound that serves as a critical building block in advanced synthetic chemistry. Its unique structure, featuring both a boronic acid and a thiol group, makes it a versatile reagent for cross-coupling reactions and bioconjugation strategies. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, materials science, and chemical biology who require reliable, high-quality building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura cross-coupling reactions to form biaryl structures.
• Bioconjugation & Protein Modification: Utilized for site-specific labeling of proteins, antibodies, and peptides via the reactive thiol group for diagnostic and therapeutic applications.
• Materials Science & Polymer Chemistry: Serves as a monomer or functionalization agent in the creation of novel polymers, hydrogels, and smart materials with responsive properties.
• Ligand Synthesis for Catalysis: Building block for constructing sophisticated ligands used in homogeneous catalysis and asymmetric synthesis.
• Chemical Biology Probes: Used in the development of activity-based probes and sensors for studying biological processes and enzyme activity.
• Surface Functionalization: Enables the modification of gold and other metal surfaces via thiol-gold chemistry for sensor and device fabrication.

Basic Information

Product Name	Boronic Acid, [4-(Mercaptomethyl)Phenyl]- (9Ci)
CAS No.	847801-60-9
Molecular Formula	C7H9BO2S
Molecular Weight	168.02 g/mol
Synonyms	(4-Mercaptomethylphenyl)boronic acid; 4-(Mercaptomethyl)benzeneboronic acid; p-(Mercaptomethyl)phenylboronic acid; [4-(Mercaptomethyl)phenyl]boronic acid; 4-(Boronic acid)-α-toluenethiol; B-[4-(Mercaptomethyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, [4-(Mercaptomethyl)Phenyl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring traceability and reliability, from research to cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to the light-sensitive and potentially moisture-sensitive nature of the compound, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.