Description

2,4-Difluoro-3-Methylbenzyl Alcohol is a versatile fluorinated benzyl alcohol derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the reactive benzylic hydroxyl group, enabling precise molecular modifications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to incorporate difluoromethylbenzene motifs into active molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Employed in the development of novel materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The benzylic alcohol can be functionalized for use in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Protecting Group Chemistry: Acts as a precursor for benzyl-based protecting groups used in multi-step synthetic sequences.

Basic Information

Product Name	2,4-Difluoro-3-Methylbenzyl Alcohol
CAS No.	847502-91-4
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	(2,4-Difluoro-3-methylphenyl)methanol; 3-Methyl-2,4-difluorobenzyl Alcohol; 2,4-Difluoro-3-methyl-benzenemethanol; α,2,4-Trifluoro-m-tolyl Alcohol; 1-(Hydroxymethyl)-2,4-difluoro-3-methylbenzene; 847502-91-4; Benzyl alcohol, 2,4-difluoro-3-methyl-
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Methylbenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.