Description

3-Formyl-6-Methoxyindole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its reactive formyl group and protected indole nitrogen. This compound matters as a critical building block for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of indole-based drug candidates, including kinase inhibitors and receptor antagonists.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile reactive sites.
• Agrochemical Synthesis: Serves as a building block for developing novel crop protection agents and plant growth regulators.
• Fine Chemical Production: Employed in the multi-step synthesis of complex organic molecules for specialty applications.
• Bioconjugation & Probe Development: The formyl group allows for selective conjugation, useful in creating biochemical probes and labeled compounds.

Basic Information

Product Name	3-Formyl-6-Methoxyindole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	847448-73-1
Molecular Formula	C15H17NO4
Molecular Weight	275.30 g/mol
Synonyms	1-Boc-6-methoxy-3-formylindole; tert-Butyl 6-methoxy-3-formyl-1H-indole-1-carboxylate; 6-Methoxy-1H-indole-3-carboxaldehyde, 1-(1,1-dimethylethyl) ester; 1-(tert-Butoxycarbonyl)-6-methoxyindole-3-carboxaldehyde; 3-Formyl-6-methoxy-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-Boc-6-methoxyindole-3-carboxaldehyde; 847448-73-1
EINECS	Contact for details

Quality Control

Our 3-Formyl-6-Methoxyindole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) with full traceability are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere, as the compound is easily oxidized and light-sensitive. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.