Description

Ethyl 8-Bromo-6-Methylimidazo[1,2-A]Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the imidazopyridine class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures with targeted biological activity. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for constructing and screening compound libraries in drug discovery programs.
• Kinase Inhibitor Synthesis: Serves as a building block for potential kinase inhibitors, a major class of targeted cancer therapies.
• CNS Drug Development: Employed in the synthesis of compounds targeting neurological disorders due to the imidazopyridine core's prevalence in this field.
• Chemical Biology Probes: Utilized to create specialized molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Ethyl 8-Bromo-6-Methylimidazo[1,2-A]Pyridine-2-Carboxylate
CAS No.	847446-55-3
Molecular Formula	C11H11BrN2O2
Molecular Weight	283.12 g/mol
Synonyms	Ethyl 8-bromo-6-methylimidazo[1,2-a]pyridine-2-carboxylate; 8-Bromo-6-methylimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-bromo-6-methyl-, ethyl ester; 847446-55-3; Ethyl 8-bromo-6-methyl-imidazo[1,2-a]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 8-Bromo-6-Methylimidazo[1,2-A]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.