Description

Methanone, [4,5-Bis[(1,1-Dimethylethyl)Amino]-2-(Trifluoromethyl)-3-Furanyl]-2-Thienyl- is a specialized organic compound featuring a unique molecular architecture combining furan and thiophene heterocycles with tert-butylamino and trifluoromethyl substituents. This structure makes it a valuable high-purity intermediate for advanced chemical synthesis, particularly in the development of novel functional materials and active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science sectors for constructing complex molecules with tailored electronic and steric properties.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Organic Electronic Materials: Acts as a precursor for conjugated molecules in organic light-emitting diodes (OLEDs) or organic photovoltaics (OPVs), leveraging its fused heterocyclic core.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, utilizing the nitrogen donor atoms from the tert-butylamino groups.
• Fluorine Chemistry Studies: A valuable substrate for investigating structure-activity relationships (SAR) in medicinal chemistry due to its defined fluorinated structure.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in bespoke synthesis projects and scale-up development.

Basic Information

Product Name	Methanone, [4,5-Bis[(1,1-Dimethylethyl)Amino]-2-(Trifluoromethyl)-3-Furanyl]-2-Thienyl-
CAS No.	845965-05-1
Molecular Formula	C19H23F3N2O2S
Molecular Weight	400.46 g/mol
Synonyms	[4,5-Bis(tert-butylamino)-2-(trifluoromethyl)-3-furanyl](2-thienyl)methanone; 2-Thienyl[4,5-bis(tert-butylamino)-2-(trifluoromethyl)-3-furanyl]methanone; (4,5-Bis((tert-butyl)amino)-2-(trifluoromethyl)furan-3-yl)(thiophen-2-yl)methanone; CAS 845965-05-1; 845965-05-1
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications, with documentation tailored to meet rigorous audit standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.