Description

Methyl 5-Bromo-2-Ureidothiophene-3-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive bromine and ureido functional groups, which enable precise molecular construction in complex chemical pathways. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways where the thiophene scaffold is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for creating functionalized polymers or organic electronic materials with specific optoelectronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions due to the reactive bromine atom.
• Academic & Contract Research: A valuable reagent for methodological studies and the construction of complex molecular libraries in academic and industrial R&D settings.

Basic Information

Product Name	Methyl 5-Bromo-2-Ureidothiophene-3-Carboxylate
CAS No.	845889-21-6
Molecular Formula	C7H7BrN2O3S
Molecular Weight	279.11 g/mol
Synonyms	Methyl 5-bromo-2-ureido-3-thiophenecarboxylate; 5-Bromo-2-ureidothiophene-3-carboxylic acid methyl ester; 3-Thiophenecarboxylic acid, 5-bromo-2-ureido-, methyl ester; 845889-21-6; Methyl 5-bromo-2-(aminocarbonylamino)thiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 5-Bromo-2-Ureidothiophene-3-Carboxylate is manufactured and tested under strict quality management systems. We ensure compliance with high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.