Description

[2-[1-(tert-Butoxycarbonyl)Piperidin-4-Yl]-5-Methyl-1,3-Thiazol-4-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting neurological or metabolic disorders.
• Protease Inhibitor Research: Used in the research and development of inhibitors for specific proteolytic enzymes, leveraging its piperidine-thiazole-acetic acid scaffold.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Custom Synthesis & Scale-Up: Supplied for custom synthesis projects, from milligram-scale research to kilogram-scale process development and cGMP manufacturing.
• Bioconjugation & Linker Chemistry: The carboxylic acid functional group allows for use in bioconjugation strategies or as a component of chemical linkers in prodrug design.

Basic Information

Product Name	[2-[1-(tert-Butoxycarbonyl)Piperidin-4-Yl]-5-Methyl-1,3-Thiazol-4-Yl]Acetic Acid
CAS No.	845885-88-3
Molecular Formula	C17H26N2O4S
Molecular Weight	354.47 g/mol
Synonyms	4-(5-Methyl-4-((carboxymethyl)thiazol-2-yl)piperidin-1-yl)carboxylic acid tert-butyl ester; 2-[1-(BOC)Piperidin-4-Yl]-5-Methyl-4-Thiazoleacetic Acid; BOC-Piperidine-Thiazole-Acetic Acid Derivative; tert-Butyl 4-(5-methyl-4-((carboxymethyl)thiazol-2-yl)piperidine-1-carboxylate; (2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-5-methyl-1,3-thiazol-4-yl)acetic acid
EINECS	Contact for details

Quality Control

Our [2-[1-(tert-Butoxycarbonyl)Piperidin-4-Yl]-5-Methyl-1,3-Thiazol-4-Yl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.