Description

4-Methyl-Thiophene-2-Amidoxime is a specialized organic intermediate featuring a thiophene ring substituted with a methyl group and an amidoxime functional group. This unique structure makes it a valuable synthon for constructing complex molecules in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. The compound, identified by CAS No. 845866-87-7, is a key building block for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, where the thiophene-amidoxime moiety can contribute to biological activity.
• Ligand Synthesis: The amidoxime group acts as an excellent chelating agent for metal ions, making this compound useful for creating catalysts and metal-organic frameworks (MOFs).
• Material Science Precursor: Employed in the research and development of advanced polymers and functional materials with specific electronic or binding properties.
• Chemical Biology Probe: Utilized as a building block for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	4-Methyl-Thiophene-2-Amidoxime
CAS No.	845866-87-7
Molecular Formula	C6H8N2OS
Molecular Weight	156.21 g/mol
Synonyms	2-Amidoxime-4-methylthiophene; 4-Methyl-2-thiophenecarboximidamide, N-hydroxy-; 4-Methylthiophene-2-carboxamidoxime; 2-(Hydroxyamino)carboximidoyl-4-methylthiophene; N-Hydroxy-4-methyl-2-thiophenecarboximidamide; 4-Methyl-2-thiophenecarboxamidoxime
EINECS	Contact for details

Quality Control

Our 4-Methyl-Thiophene-2-Amidoxime is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.