Description

4-Fluoro-2-Methylbenzenethiol is a specialized organosulfur compound featuring both a thiol (-SH) group and a fluorine substituent on a methylated benzene ring. This unique structure makes it a valuable building block in advanced organic synthesis, particularly for introducing sulfur-containing motifs with enhanced electronic properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, especially those targeting neurological disorders and cancers, where the fluorine atom can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiol group for creating sulfur bridges or as a reactive handle.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis for cross-coupling and other organic transformations.
• Material Science Research: Employed in the development of organic electronic materials, such as conductive polymers and self-assembled monolayers (SAMs), due to its ability to bind to metal surfaces.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex sulfur-containing aroma chemicals, contributing to meaty or roasted notes.

Basic Information

Product Name	4-Fluoro-2-Methylbenzenethiol
CAS No.	845823-04-3
Molecular Formula	C7H7FS
Molecular Weight	142.19 g/mol
Synonyms	2-Methyl-4-fluorobenzenethiol; 4-Fluoro-o-toluenethiol; 4-Fluoro-2-methylthiophenol; 2-Methyl-4-fluorophenyl mercaptan; 4-Fluoro-2-tolyl mercaptan; (4-Fluoro-2-methylphenyl)thiol; 845823-04-3; 4-Fluoro-2-methylbenzenethiol
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2-Methylbenzenethiol is produced and analyzed under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive testing includes identity confirmation, purity assay, and control of key impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.