Description

4-Bromo-3',3''-Dichlorotrityl Alcohol is a specialized trityl-protecting group reagent used in synthetic organic chemistry. This compound is valued for its role in the selective protection of hydroxyl groups, particularly in the synthesis of complex molecules like oligonucleotides and peptides. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for sensitive synthetic pathways.

Application

• Solid-Phase Oligonucleotide Synthesis (SPOS): As a key protecting group reagent for the 5'-hydroxyl function of nucleosides.
• Peptide Synthesis: Used for the temporary protection of serine, threonine, or tyrosine side chains during fragment condensation.
• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and prodrugs.
• Agrochemical Research: Employed in the development of novel herbicides and pesticides where selective protection is required.
• Material Science: Utilized in the synthesis of functionalized polymers and dendrimers with precise molecular architectures.
• Academic & R&D Laboratories: A valuable tool for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	4-Bromo-3',3''-Dichlorotrityl Alcohol
CAS No.	845790-85-4
Molecular Formula	C20H13BrCl2O
Molecular Weight	420.13 g/mol
Synonyms	4-Bromo-3',3''-dichlorotrityl alcohol; 4-Bromo-3',3''-dichloro-α,α-diphenylbenzenemethanol; 4-Bromo-3',3''-dichlorotrityl-OH; 4-Br-DCTr-OH; 4-Bromo-3',3''-dichlorotriphenylmethanol; 4-Bromo-3',3''-dichlorotrityl alcohol (4-Br-DCTr-OH); 4-Bromo-3',3''-dichlorotrityl protecting group reagent
EINECS	Contact for details

Quality Control

Our 4-Bromo-3',3''-Dichlorotrityl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a desiccator to protect from moisture due to potential hygroscopicity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.