Description

3,3'-Dimethoxy-4''-Fluorotrityl Alcohol is a specialized trityl-protecting group reagent, a key intermediate in modern synthetic organic chemistry. Its value lies in its selective reactivity, which enables the efficient protection of hydroxyl groups during the multi-step synthesis of complex molecules, particularly under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require high-purity building blocks for oligonucleotide and peptide synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and nucleotide analogs.
• Oligonucleotide Synthesis: Used as a protecting group reagent for the 5'-hydroxyl function in solid-phase phosphoramidite chemistry.
• Peptide Chemistry: Employed for the temporary protection of specific amino acid side chains during complex peptide assembly.
• Agrochemical Research: Serves as an intermediate in the development of novel herbicides and plant growth regulators.
• Material Science: Acts as a precursor or modifying agent in the creation of specialty polymers and dendrimers.
• Chemical Biology & Diagnostics: Utilized in the preparation of labeled probes and molecular tools for research and diagnostic applications.

Basic Information

Product Name	3,3'-Dimethoxy-4''-Fluorotrityl Alcohol
CAS No.	845790-69-4
Molecular Formula	C23H21FO3
Molecular Weight	364.41 g/mol
Synonyms	4-Fluoro-3,3'-dimethoxytrityl alcohol; 4''-Fluoro-3,3'-dimethoxytrityl alcohol; DMTr-F-OH; 4-F-DMTr-OH; [(4-Fluorophenyl)bis(3-methoxyphenyl)methyl]methanol; 1-[(4-Fluorophenyl)bis(3-methoxyphenyl)methyl]methanol; F-DMTr Alcohol; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 3,3'-Dimethoxy-4''-Fluorotrityl Alcohol is manufactured and tested under a strict quality management system. We guarantee high purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.