Description

3,3'-Dimethyl-4''-Methyltrityl Alcohol CAS NO 845790-68-3 is a specialized trityl alcohol derivative, a key intermediate in advanced organic synthesis. Its value lies in its role as a versatile protecting group precursor and building block for complex molecules, offering high selectivity and stability under specific reaction conditions. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly those working on nucleoside chemistry, oligonucleotide synthesis, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules and nucleoside analogs.
• Oligonucleotide Synthesis: Used as a precursor for protecting groups in the solid-phase synthesis of DNA and RNA fragments.
• Fine Chemical Production: Serves as a key intermediate in the manufacture of specialty chemicals and advanced materials.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new synthetic pathways.
• Protecting Group Chemistry: Utilized to introduce the trityl group, which protects hydroxyl functions during multi-step syntheses.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and catalysts for asymmetric synthesis.

Basic Information

Product Name	3,3'-Dimethyl-4''-Methyltrityl Alcohol
CAS No.	845790-68-3
Molecular Formula	C22H22O
Molecular Weight	302.41 g/mol
Synonyms	4''-Methyl-3,3'-dimethyltrityl alcohol; 4-Monomethyltrityl Alcohol (MMTr-OH); [4-(Hydroxy-di-p-tolyl-methyl)-2-methylphenyl]methanol; 4'-Methyl-4''-hydroxy-3,3''-dimethyltrityl alcohol; MMTr Alcohol; 4-Monomethoxytrityl Alcohol derivative; 4-Methyl-α,α-bis(4-methylphenyl)benzenemethanol
EINECS	Contact for details

Quality Control

Our 3,3'-Dimethyl-4''-Methyltrityl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.