Description

4,4'-Dimethyl-3''-Methyltrityl Alcohol CAS NO 845790-67-2 is a specialized trityl alcohol derivative used as a key protecting group reagent and synthetic intermediate in advanced organic synthesis. Its value lies in providing a robust, acid-labile protecting group for hydroxyl functions, enabling complex multi-step synthesis in sensitive applications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of complex drug candidates, particularly in nucleotide and oligonucleotide chemistry where selective hydroxyl protection is required.
• Protecting Group Reagent: Used to temporarily mask hydroxyl (-OH) groups during multi-step synthetic sequences, preventing unwanted side reactions.
• Agrochemical Synthesis: Serves as a building block in the production of advanced pesticides and herbicides with specific stereochemical requirements.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and performance materials where precise molecular architecture is needed.
• Academic & R&D Laboratories: A valuable tool for methodological development and the synthesis of novel chemical entities in research settings.
• Peptide & Carbohydrate Chemistry: Facilitates the selective protection of sensitive functional groups in the synthesis of biomolecules and glycoconjugates.

Basic Information

Product Name	4,4'-Dimethyl-3''-Methyltrityl Alcohol
CAS No.	845790-67-2
Molecular Formula	C23H24O
Molecular Weight	316.44 g/mol
Synonyms	3''-Methyl-4,4''-dimethyltrityl alcohol; DMT-OH (Dimethoxytrityl alcohol variant); 4,4'-Dimethyl-3''-methyltriphenylmethanol; (4,4'-Dimethyl-3''-methylphenyl)diphenylmethanol; MMTr-OH; 3'-Methyl-4,4'-dimethyltrityl alcohol; DMT Alcohol derivative; Triphenylmethanol, 4,4'-dimethyl-3''-methyl-
EINECS	Contact for details

Quality Control

Our 4,4'-Dimethyl-3''-Methyltrityl Alcohol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere such as argon or nitrogen to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.