Description

3,3'-Dimethoxy-3''-Methyltrityl Alcohol CAS NO 845790-60-5 is a specialized trityl-protected alcohol derivative, a crucial intermediate in advanced organic synthesis. Its core value lies in providing a robust, selectively cleavable protecting group for primary alcohols, enabling complex multi-step reactions in sensitive molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly in the synthesis of nucleosides, nucleotides, and other biologically active compounds where precise control over functional group reactivity is paramount.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Serves as a critical protecting group reagent in solid-phase phosphoramidite chemistry for DNA/RNA synthesizers.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products, catalysts, and specialty materials requiring orthogonal protection strategies.
• Carbohydrate Chemistry: Protects primary hydroxyl groups in sugar and glycoside synthesis, allowing for selective modification at other positions.
• Peptide Chemistry: Can be employed in the protection of serine or threonine side chains during peptide synthesis.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists exploring new synthetic routes and developing scalable manufacturing processes.

Basic Information

Product Name	3,3'-Dimethoxy-3''-Methyltrityl Alcohol
CAS No.	845790-60-5
Molecular Formula	C23H24O3
Molecular Weight	348.44 g/mol
Synonyms	3,3'-Dimethoxy-3''-methyltrityl alcohol; DMT-OH (Dimethoxytrityl alcohol); 4,4'-Dimethoxy-3'-methyltrityl alcohol; (4,4'-Dimethoxyphenyl)(2-methoxyphenyl)phenylmethanol; MMTr-OH; 3'-Methyl-4,4'-dimethoxytrityl alcohol; Hydroxy(4,4'-dimethoxy-3'-methyltriphenyl)methane
EINECS	Contact for details

Quality Control

Our 3,3'-Dimethoxy-3''-Methyltrityl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.