Description

2-Thiazolemethanol, 4-Ethynyl- is a specialized heterocyclic building block featuring both a thiazole core and a terminal alkyne functional group. This unique molecular architecture makes it a highly valuable intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical researchers for constructing novel active ingredients and by material scientists exploring new functional polymers. The compound is supplied with the CAS registry number 845658-60-8.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the design and synthesis of novel drug candidates, particularly for targeted therapies.
• Agrochemical Research: Used in creating new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Material Science: Acts as a monomer or cross-linking agent in the development of advanced polymers with specific electronic or mechanical properties.
• Chemical Biology: Employed in bioconjugation and probe development due to its reactive ethynyl group for click chemistry applications.
• Ligand Synthesis: Utilized in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A fundamental building block for exploratory synthetic chemistry across multiple disciplines.

Basic Information

Product Name	2-Thiazolemethanol, 4-Ethynyl-
CAS No.	845658-60-8
Molecular Formula	C6H5NOS
Molecular Weight	139.18 g/mol
Synonyms	4-Ethynyl-2-thiazolemethanol; 4-Ethynylthiazole-2-methanol; (4-Ethynyl-1,3-thiazol-2-yl)methanol; 2-(Hydroxymethyl)-4-ethynylthiazole; 4-Ethynyl-2-(hydroxymethyl)thiazole; 4-Ethynyl-2-thiazolylmethanol
EINECS	Contact for details

Quality Control

Our 2-Thiazolemethanol, 4-Ethynyl- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.