Description

1-Pivaloylindole-3-Carbaldehyde is a high-purity, versatile indole derivative used as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring both a pivaloyl-protected indole core and a reactive aldehyde group, makes it an essential building block for constructing complex heterocyclic frameworks. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel indole-based drug candidates, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the indole scaffold.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, particularly in palladium-catalyzed cross-coupling and multi-component reactions.
• Chemical Biology: Employed as a probe or linker in the design and synthesis of chemical tools for studying biological systems.

Basic Information

Product Name	1-Pivaloylindole-3-Carbaldehyde
CAS No.	845619-73-0
Molecular Formula	C14H15NO2
Molecular Weight	229.27 g/mol
Synonyms	1-Pivaloyl-1H-indole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 1-(2,2-dimethyl-1-oxopropoxy)-; 1-(2,2-Dimethylpropanoyl)indole-3-carbaldehyde; 1-Pivaloylindole-3-carboxaldehyde; 3-Formyl-1-pivaloylindole; 1-Pivaloyl-3-formylindole; PIVALOYL INDOLE-3-CARBALDEHYDE; 1-(2,2-Dimethylpropionyl)-1H-indole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-Pivaloylindole-3-Carbaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.