Description

2-(tert-Butoxycarbonyl)-1,2,3,4-Tetrahydro-6-Hydroxyisoquinoline-3-Carboxylic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in medicinal chemistry, process development, and fine chemical production who require reliable, high-quality intermediates for peptide mimetics and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and cardiovascular diseases.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs with enhanced metabolic stability and bioavailability.
• Combinatorial Chemistry: Serves as a versatile scaffold in library synthesis for high-throughput screening and drug discovery programs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of synthetic routes for Active Pharmaceutical Ingredients (APIs) at pilot and commercial scales.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry.
• Fine Chemical Synthesis: Intermediate for the production of specialty chemicals with complex isoquinoline-based architectures.

Basic Information

Item	Details
Product Name	2-(tert-Butoxycarbonyl)-1,2,3,4-Tetrahydro-6-Hydroxyisoquinoline-3-Carboxylic Acid
CAS No.	845552-56-9
Molecular Formula	C15H19NO5
Molecular Weight	293.32 g/mol
Synonyms	Boc-Tic(6-OH)-OH; 2-[(tert-Butoxy)carbonyl]-1,2,3,4-tetrahydro-6-hydroxy-3-isoquinolinecarboxylic acid; 6-Hydroxy-Boc-Tic-OH; (3S)-2-[(2-Methylpropan-2-yl)oxycarbonyl]-1,2,3,4-tetrahydro-6-hydroxyisoquinoline-3-carboxylic acid; 2-(Boc)-1,2,3,4-tetrahydro-6-hydroxyisoquinoline-3-carboxylic acid; Boc-6-hydroxy-Tic-OH; N-Boc-6-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxycarbonyl)-1,2,3,4-Tetrahydro-6-Hydroxyisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development through to commercial manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.