Description

Methyl 3-Amino-4-[(4-Chlorophenyl)Sulfonyl]-5-(Methylthio)Thiophene-2-Carboxylate CAS NO 845266-18-4 is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring a thiophene core with amino, sulfonyl, and ester functionalities, makes it a versatile intermediate for constructing sophisticated target molecules. This compound is primarily sought by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors where the thiophene-sulfonyl pharmacophore is critical.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Chemistry: Used in the research and development of advanced organic electronic materials, such as conductive polymers or non-linear optical (NLO) materials.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.
• Academic & Institutional Research: Employed in university and institutional labs for methodological studies in heterocyclic and organosulfur chemistry.

Basic Information

Product Name	Methyl 3-Amino-4-[(4-Chlorophenyl)Sulfonyl]-5-(Methylthio)Thiophene-2-Carboxylate
CAS No.	845266-18-4
Molecular Formula	C13H12ClNO4S3
Molecular Weight	377.88 g/mol
Synonyms	Methyl 3-amino-4-[(4-chlorophenyl)sulfonyl]-5-(methylthio)thiophene-2-carboxylate; 3-Amino-4-[(4-chlorophenyl)sulfonyl]-5-(methylthio)thiophene-2-carboxylic acid methyl ester; Thiophene-2-carboxylic acid, 3-amino-4-[(4-chlorophenyl)sulfonyl]-5-(methylthio)-, methyl ester; Methyl 3-amino-5-(methylthio)-4-[(4-chlorophenyl)sulfonyl]thiophene-2-carboxylate; 845266-18-4; 4-[(4-Chlorophenyl)sulfonyl]-5-(methylthio)-3-aminothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-4-[(4-Chlorophenyl)Sulfonyl]-5-(Methylthio)Thiophene-2-Carboxylate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.