Description

3-Chloro-3',5-Difluorobenzhydrol is a high-purity fluorinated and chlorinated benzhydrol derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique halogenated structure provides a reactive scaffold for constructing complex molecules, enabling the development of novel active ingredients. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluorobenzhydrol moiety imparts desired biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer Science: Acts as a monomer or chain modifier in the synthesis of specialty polymers with enhanced thermal and chemical resistance.
• Organic Synthesis Reagent: A versatile reagent for introducing the 3-chloro-3',5-difluorobenzhydryl group into various molecular architectures via coupling or substitution reactions.
• Material Science Research: Utilized in R&D for creating novel organic electronic materials and advanced coatings.

Basic Information

Product Name	3-Chloro-3',5-Difluorobenzhydrol
CAS No.	844683-51-8
Molecular Formula	C13H9ClF2O
Molecular Weight	254.66 g/mol
Synonyms	(3-Chlorophenyl)(3,5-difluorophenyl)methanol; 1-(3-Chlorophenyl)-1-(3,5-difluorophenyl)methanol; Benzhydrol, 3-chloro-3',5-difluoro-; 3-Chloro-3',5-difluorodiphenylmethanol; α-(3-Chlorophenyl)-α-(3,5-difluorophenyl)methanol; (3,5-Difluorophenyl)(3-chlorophenyl)carbinol
EINECS	Contact for details

Quality Control

Our 3-Chloro-3',5-Difluorobenzhydrol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.