Description

3-(5-Fluoro-1H-Indol-3-Yl)-2-Methyl-Propionic Acid is a high-purity fluorinated indole derivative, a critical building block in modern pharmaceutical and agrochemical research. This compound is valued for its unique molecular scaffold, which is essential for synthesizing novel active ingredients with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used to develop new herbicides and plant growth regulators leveraging the indole core structure.
• Biochemical Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme inhibition and receptor binding.
• Peptidomimetics Development: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.
• Material Science: Potential monomer or additive for creating specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	3-(5-Fluoro-1H-Indol-3-Yl)-2-Methyl-Propionic Acid
CAS No.	843652-71-1
Molecular Formula	C₁₂H₁₂FNO₂
Molecular Weight	221.23 g/mol
Synonyms	2-Methyl-3-(5-fluoro-1H-indol-3-yl)propanoic acid; 5-Fluoro-α-methyl-1H-indole-3-propanoic acid; 3-(5-Fluoroindol-3-yl)-2-methylpropionic acid; 843652-71-1; 5-Fluoro-α-methyl-1H-indole-3-propionic acid; 2-Methyl-3-(5-fluoro-1H-indol-3-yl)propionic acid; 3-(5-Fluoro-1H-indol-3-yl)-2-methylpropanoic acid
EINECS	Contact for details

Quality Control

Our 3-(5-Fluoro-1H-Indol-3-Yl)-2-Methyl-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.