Description

3-(2-Chloro-Acetylamino)-6-Methoxy-1H-Indole-2-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant synthetic utility. This compound is valued for its role as a key building block in the synthesis of complex heterocyclic molecules, particularly those with indole-based pharmacophores. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the indole scaffold for biological activity.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing complex heterocyclic systems in academic and industrial R&D laboratories.
• Bioconjugation & Probe Development: The reactive chloroacetyl group makes it suitable for creating chemical probes and bioconjugates for biochemical and diagnostic applications.
• Material Science Research: Potential use in the synthesis of organic electronic materials and specialty dyes due to its conjugated indole structure.

Basic Information

Item	Details
Product Name	3-(2-Chloro-Acetylamino)-6-Methoxy-1H-Indole-2-Carboxylic Acid Methyl Ester
CAS No.	843638-66-4
Molecular Formula	C13H13ClN2O4
Molecular Weight	296.71 g/mol
Synonyms	Methyl 3-[(2-chloroacetyl)amino]-6-methoxy-1H-indole-2-carboxylate; 3-(2-Chloroacetamido)-6-methoxy-1H-indole-2-carboxylic acid methyl ester; 6-Methoxy-3-(2-chloroacetylamino)-1H-indole-2-carboxylic acid methyl ester; 843638-66-4; 3-(2-Chloroacetylamino)-6-methoxyindole-2-carboxylic acid methyl ester; Methyl 3-(2-chloroacetamido)-6-methoxy-1H-indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 3-[(2-chloroacetyl)amino]-6-methoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our production of 3-(2-Chloro-Acetylamino)-6-Methoxy-1H-Indole-2-Carboxylic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.