Description

3-(2-Chloro-Acetylamino)-1H-Indole-2-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of indole-based drug candidates, including potential kinase inhibitors and receptor antagonists.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Agrochemical Synthesis: Serves as a building block for developing novel crop protection agents and pesticides.
• Chemical Biology: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.

Basic Information

Product Name	3-(2-Chloro-Acetylamino)-1H-Indole-2-Carboxylic Acid Methyl Ester
CAS No.	843615-63-4
Molecular Formula	C13H11ClN2O3
Molecular Weight	278.69 g/mol
Synonyms	Methyl 3-[(2-chloroacetyl)amino]-1H-indole-2-carboxylate; 3-(2-Chloroacetamido)-1H-indole-2-carboxylic acid methyl ester; 2-Chloro-N-(2-(methoxycarbonyl)-1H-indol-3-yl)acetamide; 843615-63-4; 3-(2-Chloroacetylamino)indole-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-(2-Chloro-Acetylamino)-1H-Indole-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.