Description

5-Fluoro-3-Methyl-1H-Indole-2-Carbaldehyde is a versatile and high-value fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a fluorine substituent and an aldehyde functional group, makes it an essential precursor for constructing complex heterocyclic compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity of the fluorinated indole scaffold.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-rich indole core.
• Academic & Contract Research: Serves as a fundamental building block in medicinal chemistry and organic synthesis laboratories for method development and library synthesis.
• Bioconjugation & Probe Development: The reactive aldehyde group allows for use in creating fluorescent probes or bioconjugates for biochemical applications.

Basic Information

Product Name	5-Fluoro-3-Methyl-1H-Indole-2-Carbaldehyde
CAS No.	842972-09-2
Molecular Formula	C10H8FNO
Molecular Weight	177.18 g/mol
Synonyms	5-Fluoro-3-methyl-1H-indole-2-carboxaldehyde; 2-Formyl-5-fluoro-3-methylindole; 5-Fluoro-3-methylindole-2-carbaldehyde; 1H-Indole-2-carboxaldehyde, 5-fluoro-3-methyl-; 842972-09-2; 5-Fluoro-3-methyl-1H-indole-2-carboxaldehyde; 3-Methyl-5-fluoroindole-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-Methyl-1H-Indole-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.