Description

4-(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-4-Oxo-Butyric Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel isoquinoline-based drug candidates for various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• API Synthesis: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Research: Potential tool compound for studying biological pathways and enzyme interactions related to its core structure.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing of high-value specialty chemicals.

Basic Information

Product Name	4-(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-4-Oxo-Butyric Acid
CAS No.	842955-83-3
Molecular Formula	C15H17NO5
Molecular Weight	291.30 g/mol
Synonyms	4-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)-4-oxobutanoic acid; 4-Oxo-4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)butanoic acid; Butanoic acid, 4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-4-oxo-; 842955-83-3; 4-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)butanoic acid
EINECS	Contact for details

Quality Control

Our 4-(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinolin-2-Yl)-4-Oxo-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.