Description

3-Chloro-4-Fluorobenzhydrol is a high-purity fluorinated and chlorinated benzhydrol derivative, serving as a critical chiral intermediate in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex pharmacophores and fine-tuning the physical properties of target molecules. This compound is primarily needed by research and development laboratories, as well as production facilities, in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and chlorine substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies, contributing to improved performance and durability.
• Chiral Ligand & Catalyst Development: Utilized in asymmetric synthesis research to develop new catalysts and ligands for stereoselective reactions.
• Polymer Modification: Acts as a monomer or modifier to introduce specific functional groups into polymer chains, altering thermal and chemical resistance.
• Organic Synthesis Research: A versatile reagent in academic and industrial R&D for constructing complex, multi-substituted aromatic systems.

Basic Information

Product Name	3-Chloro-4-Fluorobenzhydrol
CAS No.	842140-64-1
Molecular Formula	C13H10ClFO
Molecular Weight	236.67 g/mol
Synonyms	(3-Chloro-4-fluorophenyl)(phenyl)methanol; α-(3-Chloro-4-fluorophenyl)benzenemethanol; Benzhydrol, 3-chloro-4-fluoro-; 3-Chloro-4-fluoro-α-phenylbenzenemethanol; 842140-64-1; (3-Chloro-4-fluoro-phenyl)-phenyl-methanol
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorobenzhydrol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.