Description

4-Chloro-3-Fluoro-4'-Methylbenzhydrol CAS NO 842140-55-0 is a high-purity, halogenated benzhydrol derivative that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which is designed for the efficient construction of complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a sophisticated intermediate in the production of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in academic and industrial research for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.
• Chemical Research: Used in methodological studies and as a reference standard in analytical laboratories for method development and validation.

Basic Information

Product Name	4-Chloro-3-Fluoro-4'-Methylbenzhydrol
CAS No.	842140-55-0
Molecular Formula	C14H12ClFO
Molecular Weight	250.70 g/mol
Synonyms	(4-Chloro-3-fluorophenyl)(4-methylphenyl)methanol; Benzhydrol, 4-chloro-3-fluoro-4'-methyl-; 4'-Methyl-4-chloro-3-fluorobenzhydrol; α-(4-Chloro-3-fluorophenyl)-4-methylbenzenemethanol; (4-Methylphenyl)(4-chloro-3-fluorophenyl)methanol
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-Fluoro-4'-Methylbenzhydrol is produced under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent batch-to-batch performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.