Description

2-Bromo-3-(3,4-Difluorophenyl)-1-Propene is a high-value, halogenated organic building block characterized by its bromo-alkene and difluorophenyl functional groups. This compound is critical for advanced organic synthesis, enabling the introduction of both fluorine atoms and a versatile bromo-alkene moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science: Acts as a monomer or cross-linking agent in the research of specialty polymers and advanced materials with unique electronic or surface properties.
• Cross-Coupling Reactions: The bromo-alkene group makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings for carbon-carbon bond formation.
• Fluorine Chemistry: A valuable reagent for introducing the 3,4-difluorophenyl motif into molecules, a common pharmacophore in medicinal chemistry to improve lipophilicity and membrane permeability.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex, fluorinated organic frameworks and exploring new synthetic methodologies.

Basic Information

Product Name	2-Bromo-3-(3,4-Difluorophenyl)-1-Propene
CAS No.	842140-34-5
Molecular Formula	C9H7BrF2
Molecular Weight	233.05 g/mol
Synonyms	1-Propene, 2-bromo-3-(3,4-difluorophenyl)-; 2-Bromo-3-(3,4-difluorophenyl)prop-1-ene; 3-(3,4-Difluorophenyl)-2-bromoprop-1-ene; (2-Bromoallyl)-3,4-difluorobenzene; 3,4-Difluoro-2-bromoallylbenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(3,4-Difluorophenyl)-1-Propene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C/59-77°F). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.