Description

2-Bromo-3-(4-Chloro-3-Fluorophenyl)-1-Propene is a high-value halogenated aromatic building block with significant synthetic utility. This compound is essential for advanced organic synthesis, particularly in constructing complex molecular architectures for pharmaceutical and agrochemical research. It is primarily used by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries to introduce specific halogenated phenylpropene motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Serves as a critical building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of advanced organic electronic materials, including OLEDs and semiconductors, due to its halogenated aromatic structure.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl and conjugated systems.
• Ligand & Catalyst Development: Employed in the synthesis of specialized phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.

Basic Information

Product Name	2-Bromo-3-(4-Chloro-3-Fluorophenyl)-1-Propene
CAS No.	842140-30-1
Molecular Formula	C9H7BrClF
Molecular Weight	249.51 g/mol
Synonyms	1-Propene, 2-bromo-3-(4-chloro-3-fluorophenyl)-; 2-Bromo-3-(4-chloro-3-fluorophenyl)prop-1-ene; (4-Chloro-3-fluorophenyl)-2-bromopropene; 3-(4-Chloro-3-fluorophenyl)-2-bromoprop-1-ene; 2-Bromo-1-(4-chloro-3-fluorophenyl)propene; 842140-30-1; 4-Chloro-3-fluoro-β-bromostyrene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-(4-Chloro-3-Fluorophenyl)-1-Propene undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and development. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.