Description

5-Bromo-3-Chlorothiophene-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in its unique halogenated thiophene structure, which serves as a versatile precursor for constructing complex molecules with tailored electronic and biological properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its halogenated heterocycle for bioactivity.
• Material Science Precursor: Serves as a building block for conjugated polymers and organic semiconductors used in OLEDs, organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-organic frameworks (MOFs) and catalysts for cross-coupling reactions.
• Chemical Research: A valuable reagent for academic and industrial research in synthetic methodology and heterocyclic chemistry.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the thiophene core contributes to color and stability properties.

Basic Information

Product Name	5-Bromo-3-Chlorothiophene-2-Carboxylic Acid
CAS No.	842135-76-6
Molecular Formula	C5H2BrClO2S
Molecular Weight	241.49 g/mol
Synonyms	2-Bromo-4-chlorothiophene-5-carboxylic acid; 3-Chloro-5-bromothiophene-2-carboxylic acid; 5-Bromo-3-chloro-2-thiophenecarboxylic acid; 2-Thiophenecarboxylic acid, 5-bromo-3-chloro-; 842135-76-6; 5-Br-3-Cl-thiophene-2-COOH
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-Chlorothiophene-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. We provide detailed Certificates of Analysis (COA) with every shipment, and our quality systems support compliance with cGMP and ISO standards for research and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry and inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.