Description

1-Bromo-4-[(4-Chlorophenyl)Ethynyl]Benzene is a high-purity, diarylacetylene-based organic intermediate of significant importance in advanced chemical synthesis. Its rigid, conjugated structure makes it a valuable building block for the development of functional materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or requiring rigid, linear spacers.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides that leverage its halogenated diarylacetylene core.
• Organic Electronic Materials: Serves as a precursor for organic semiconductors, liquid crystals, and light-emitting materials due to its extended π-conjugation and electron-accepting properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of high-performance, thermally stable polymers and dendrimers.
• Chemical Research & Development: A versatile tool for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions in academic and industrial labs.

Basic Information

Product Name	1-Bromo-4-[(4-Chlorophenyl)Ethynyl]Benzene
CAS No.	832744-28-2
Molecular Formula	C14H8BrCl
Molecular Weight	291.57 g/mol
Synonyms	4-Bromo-4'-chlorodiphenylacetylene; 1-Bromo-4-[(4-chlorophenyl)ethynyl]benzene; 4-Bromo-4'-chlorotolan; 4-Chloro-4'-bromodiphenylacetylene; p-Bromo-p'-chlorodiphenylacetylene; (4-Bromophenyl)(4-chlorophenyl)acetylene; 832744-28-2 (CAS)
EINECS	Contact for details

Quality Control

Our production of 1-Bromo-4-[(4-Chlorophenyl)Ethynyl]Benzene adheres to stringent in-process controls and final batch release testing. We guarantee high chemical purity and lot-to-lot consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.