Description

1-n-Boc-Pyrrole-3-Boronic Acid is a high-purity, protected heterocyclic boronic acid building block essential for modern synthetic chemistry. Its core value lies in enabling efficient, selective cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing pyrrole or indole cores.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for forming carbon-carbon bonds with aryl/heteroaryl halides, enabling library synthesis and lead optimization.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Material Science: Employed in the creation of organic electronic materials, such as conductive polymers and organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Facilitates the modular construction of complex molecules for targeted protein degradation and other biological probes.
• Academic & Contract Research: A valuable reagent for methodological development and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	1-n-Boc-Pyrrole-3-Boronic Acid
CAS No.	832697-40-2
Molecular Formula	C9H14BNO4
Molecular Weight	211.03 g/mol
Synonyms	1-Boc-3-Pyrroleboronic Acid; 1-(tert-Butoxycarbonyl)-1H-pyrrole-3-boronic Acid; 3-Borono-1-[(2-methyl-2-propanyl)oxycarbonyl]-1H-pyrrole; tert-Butyl 3-boronopyrrole-1-carboxylate; 1H-Pyrrole-1-carboxylic acid, 3-borono-, 1,1-dimethylethyl ester; 1-Boc-pyrrol-3-ylboronic acid; N-Boc-pyrrole-3-boronic acid; 1-N-Boc-pyrrole-3-boronic acid pinacol ester (common derivative).
EINECS	Contact for details

Quality Control

Our 1-n-Boc-Pyrrole-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C under an inert atmosphere (argon or nitrogen) due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to equilibrate to room temperature before opening to minimize condensation and exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.