Description

2-Amino-4-Methyl-5-Propylcarbamoyl-Thiophene-3-Carboxylic Acid Methyl Ester is a high-purity, specialized thiophene derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both amino and carbamoyl functionalities, makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating compounds with targeted biological or physical properties.

Application

This versatile thiophene-based intermediate is engineered for high-value synthesis applications across several advanced industries.

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, anti-inflammatory drugs, and other therapeutic molecules.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and fungicides where the thiophene scaffold imparts specific biological activity.
• Material Science Research: Serves as a monomer or building block for developing advanced polymers, organic semiconductors, and liquid crystals with tailored electronic or optical properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new heterocyclic chemistry, creating compound libraries for screening, and developing novel synthetic methodologies.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	2-Amino-4-Methyl-5-Propylcarbamoyl-Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	832106-18-0
Molecular Formula	C11H16N2O3S
Molecular Weight	256.32 g/mol
Synonyms	Methyl 2-amino-4-methyl-5-[(propylamino)carbonyl]thiophene-3-carboxylate; 2-Amino-4-methyl-5-(propylcarbamoyl)thiophene-3-carboxylic acid methyl ester; 5-Propylcarbamoyl-2-amino-4-methyl-thiophene-3-carboxylic acid methyl ester; Thiophene-3-carboxylic acid, 2-amino-4-methyl-5-[(propylamino)carbonyl]-, methyl ester; AMTCME (abbreviation); CAS 832106-18-0
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-Methyl-5-Propylcarbamoyl-Thiophene-3-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure consistency and meet the exacting standards required for synthetic intermediates. Certificates of Analysis (COA) detailing all critical specifications are provided with every shipment to guarantee traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.