Description

2-Methyl-4-(Quinolin-4-Yl)But-3-Yn-2-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique alkyne-substituted quinoline structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and anti-infective research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Organic Synthesis Building Block: Used in coupling reactions, such as Sonogashira or Click chemistry, to introduce the quinoline-alkynol moiety into larger molecular frameworks.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents with specific biological activity.
• Material Science Research: Investigated for use in the development of organic electronic materials or metal-organic frameworks (MOFs) due to its conjugated system.

Basic Information

Product Name	2-Methyl-4-(Quinolin-4-Yl)But-3-Yn-2-Ol
CAS No.	831235-65-5
Molecular Formula	C₁₄H₁₃NO
Molecular Weight	211.26 g/mol
Synonyms	4-(4-Quinolyl)-2-methylbut-3-yn-2-ol; 2-Methyl-4-(4-quinolyl)-3-butyn-2-ol; 4-(2-Hydroxy-2-methylbut-3-yn-4-yl)quinoline; 4-(3-Hydroxy-3-methylbut-1-yn-1-yl)quinoline; 2-Methyl-4-(quinolin-4-yl)but-3-yn-2-ol; Quinolin-4-yl alkyne alcohol derivative
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(Quinolin-4-Yl)But-3-Yn-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.