Description

Thiazole, 4-Methyl-2-[(3R,5S)-5-Methyl-1-oxaspiro[2.5]oct-2-yl]-, Rel- (9Ci) is a high-purity, stereochemically defined organic intermediate with a complex spirocyclic and thiazole-containing structure. This compound is of significant value for advanced pharmaceutical research and fine chemical synthesis, where precise molecular architecture is critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new pesticides or herbicides where the thiazole and spirocyclic motifs can impart unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor or framework for creating specialized ligands used in asymmetric catalysis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or electronic properties.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological studies in organic synthesis and medicinal chemistry.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex, high-value molecules for various industrial applications.

Basic Information

Product Name	Thiazole, 4-Methyl-2-[(3R,5S)-5-Methyl-1-oxaspiro[2.5]oct-2-yl]-, Rel- (9Ci)
CAS No.	831224-85-2
Molecular Formula	C12H17NOS
Molecular Weight	223.33 g/mol
Synonyms	rel-(2R,5S)-5-Methyl-2-[4-methyl-1,3-thiazol-2-yl]-1-oxaspiro[2.5]octane; 4-Methyl-2-[(3R,5S)-5-methyl-1-oxaspiro[2.5]oct-2-yl]thiazole; (3R,5S)-5-Methyl-1-oxaspiro[2.5]oct-2-yl-4-methylthiazole; 831224-85-2; Spiro[cyclopropane-1,6'-[2]oxaspiro[2.5]octane] thiazole derivative
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) that detail purity, stereochemical integrity, and impurity profiles, ensuring compliance with rigorous R&D and cGMP standards for pharmaceutical development. Our quality systems are designed to guarantee batch-to-batch consistency and traceability for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity over time.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.