Description

5-(4-Bromo-5-Ethylthien-2-Yl)-4-Ethyl-4H-1,2,4-Triazole-3-Thiol is a high-value heterocyclic building block featuring a fused thiophene-triazole-thiol core structure. This compound matters for its role as a critical synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals, particularly for creating molecules with specific biological activity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and anticancer research programs.
• Agrochemical Synthesis: Used in the development of next-generation fungicides, herbicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology Probe Development: Utilized in creating tool compounds and probes for studying enzyme function and biological pathways due to its reactive thiol and halogenated groups.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-(4-Bromo-5-Ethylthien-2-Yl)-4-Ethyl-4H-1,2,4-Triazole-3-Thiol
CAS No.	828277-47-0
Molecular Formula	C10H12BrN3S2
Molecular Weight	318.26 g/mol
Synonyms	4-Ethyl-5-(4-bromo-5-ethyl-2-thienyl)-4H-1,2,4-triazole-3-thiol; 5-(4-Bromo-5-ethyl-2-thienyl)-4-ethyl-1,2,4-triazole-3-thiol; 4-Ethyl-5-(4-bromo-5-ethylthiophen-2-yl)-4H-1,2,4-triazole-3-thiol; 828277-47-0; 5-(4-Bromo-5-ethylthien-2-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol; 4-Ethyl-5-(5-ethyl-4-bromothiophen-2-yl)-4H-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our 5-(4-Bromo-5-Ethylthien-2-Yl)-4-Ethyl-4H-1,2,4-Triazole-3-Thiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.