Description

6H-Cyclopenta[B]Thiophen-6-One,4,5-Dihydro-5-Hydroxy-,(5S)-(9Ci) is a high-purity chiral intermediate featuring a fused cyclopenta[b]thiophene core structure. This compound is of significant value for its role in the synthesis of complex, biologically active molecules, offering precise stereochemical control. It is primarily sought after by research institutions and pharmaceutical development companies engaged in advanced organic synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects targeting various disease pathways.
• Asymmetric Synthesis: Serves as a precursor in catalytic asymmetric reactions to construct enantiomerically pure compounds for high-value applications.
• Chemical Reference Standard: Employed as an analytical standard for method development, quality control, and regulatory submissions in pharmaceutical manufacturing.
• Advanced Material Research: Investigated as a monomer or precursor for specialty polymers and organic electronic materials due to its fused thiophene structure.

Basic Information

Product Name	6H-Cyclopenta[B]Thiophen-6-One,4,5-Dihydro-5-Hydroxy-,(5S)-(9Ci)
CAS No.	827609-18-7
Molecular Formula	C7H6O2S
Molecular Weight	154.19 g/mol
Synonyms	(5S)-4,5-Dihydro-5-hydroxy-6H-cyclopenta[b]thiophen-6-one; (5S)-5-Hydroxy-4,5-dihydro-6H-cyclopenta[b]thiophen-6-one; 6H-Cyclopenta[b]thiophen-6-one, 4,5-dihydro-5-hydroxy-, (5S)-; (S)-5-Hydroxy-4,5-dihydrocyclopenta[b]thiophen-6(6H)-one; 827609-18-7; SCHEMBL218424; AKOS025147324
EINECS	Contact for details

Quality Control

Our 6H-Cyclopenta[B]Thiophen-6-One,4,5-Dihydro-5-Hydroxy-,(5S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); ensure containers are sealed under an inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.