Description

1-Propanone,2-Hydroxy-1-(1-Methyl-1H-Indol-2-Yl)-,(2R)-(9Ci) is a chiral indole derivative of significant interest in advanced organic synthesis. This compound serves as a versatile chiral building block for the construction of complex molecules with potential biological activity. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, asymmetric synthesis, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Employed in stereoselective reactions to create enantiomerically pure compounds for high-value fine chemicals.
• Biochemical Research: Potential use as a tool compound or probe in enzymatic and receptor binding studies due to its indole moiety.
• Academic Research: Serves as a reference standard or starting material in university laboratories for methodological development in organic chemistry.

Basic Information

Product Name	1-Propanone,2-Hydroxy-1-(1-Methyl-1H-Indol-2-Yl)-,(2R)-(9Ci)
CAS No.	827322-61-2
Molecular Formula	C₁₃H₁₅NO₂
Molecular Weight	217.26 g/mol
Synonyms	(2R)-2-Hydroxy-1-(1-methyl-1H-indol-2-yl)propan-1-one; 2-Hydroxy-1-(1-methyl-1H-indol-2-yl)-1-propanone, (2R)-; (R)-2-Hydroxy-1-(1-methyl-1H-indol-2-yl)propan-1-one; 1-Propanone, 2-hydroxy-1-(1-methyl-1H-indol-2-yl)-, (2R)-; 827322-61-2; Chiral Indole Ketone; 1-Methyl-2-(1-oxo-2-hydroxypropyl)indole, (R)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.