Description

1H-Pyrido[3,4-B]Indole-3-Carboxylicacid,2,3,4,9-Tetrahydro-1-Methyl-,(3R)-(9Ci) is a high-purity chiral intermediate of significant interest in advanced pharmaceutical synthesis. This compound matters because its complex, fused heterocyclic structure serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly in the fields of neurology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and novel APIs.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies in drug discovery programs.
• Process Chemistry Development: Serves as a standard or starting material for optimizing synthetic routes and scaling up production.
• Asymmetric Synthesis: Utilized in reactions requiring high enantiomeric purity due to its defined (3R) stereochemistry.
• Reference Standard: Acts as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1H-Pyrido[3,4-B]Indole-3-Carboxylicacid,2,3,4,9-Tetrahydro-1-Methyl-,(3R)-(9Ci)
CAS No.	827304-63-2
Molecular Formula	C₁₄H₁₄N₂O₂
Molecular Weight	242.27 g/mol
Synonyms	(3R)-1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid; (R)-1-Methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid; Tetrahydroharman-3-carboxylic acid (R-enantiomer); 9H-Pyrido[3,4-b]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-methyl-, (3R)-; (R)-1-Methyl-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request. We adhere to a quality management system suitable for supplying materials for research and development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.