Description

Benzo[B]Thiophene-2-Carboxylic Acid, 6-Fluoro-4-Methyl- is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and material science industries seeking to incorporate the benzo[b]thiophene scaffold with specific fluorine and methyl substitutions.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science: Acts as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials with tailored optoelectronic properties.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in the study of enzyme mechanisms and protein interactions due to its distinctive structural motif.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry, including cross-coupling reactions and fluorination studies.

Basic Information

Product Name	Benzo[B]Thiophene-2-Carboxylic Acid, 6-Fluoro-4-Methyl-
CAS No.	826995-61-3
Molecular Formula	C10H7FO2S
Molecular Weight	210.22 g/mol
Synonyms	6-Fluoro-4-methylbenzo[b]thiophene-2-carboxylic acid; 4-Methyl-6-fluorobenzo[b]thiophene-2-carboxylic acid; 6-Fluoro-4-methyl-1-benzothiophene-2-carboxylic acid; 2-Carboxy-6-fluoro-4-methylbenzo[b]thiophene; 826995-61-3; 6-Fluoro-4-methylbenzo[b]thiophene-2-carboxylate (anion form)
EINECS	Contact for details

Quality Control

Every batch of Benzo[B]Thiophene-2-Carboxylic Acid, 6-Fluoro-4-Methyl- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.