Description

Benzo[B]Thiophene-2-Carboxylic Acid, 4-Bromo-5-Fluoro- is a high-purity, halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Development: Used as a building block for creating new herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Synthesis: A versatile reagent for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to introduce complex thiophene motifs.
• Academic & Contract Research: Essential for medicinal chemistry and process chemistry research in academic institutions and CROs (Contract Research Organizations).

Basic Information

Product Name	Benzo[B]Thiophene-2-Carboxylic Acid, 4-Bromo-5-Fluoro-
CAS No.	826995-59-9
Molecular Formula	C9H4BrFO2S
Molecular Weight	275.09 g/mol
Synonyms	4-Bromo-5-fluorobenzo[b]thiophene-2-carboxylic acid; 4-Bromo-5-fluoro-1-benzothiophene-2-carboxylic acid; 5-Fluoro-4-bromobenzo[b]thiophene-2-carboxylic acid; 826995-59-9; Benzo[b]thiophene-2-carboxylic acid, 4-bromo-5-fluoro-; 4-Bromo-5-fluorobenzo[b]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Benzo[B]Thiophene-2-Carboxylic Acid, 4-Bromo-5-Fluoro- is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.